In Vitro Inhibition of Human Sperm Creatine Kinase by Nicotine, Cotinine and Cadmium, as a Mechanism in Smoker Men Infertility

in vitro inhibition of human sperm creatine kinase by nicotine, cotinine and cadmium, as a mechanism in smoker men infertility

background: nicotine, cotinine and cadmium are harmful components of cigarettes that have an effect on human reproductive function. although the effects of cigarette smoke on male reproductive function is characterized in several articles its mechanism of action is still unknown. in the present study, we investigate the effect of nicotine, cotinine and cadmium on human sperm creatine kinase act...

In vitro Effect of Lead, Silver, Tin, Mercury, Indium and Bismuth on Human Sperm Creatine Kinase Activity: a Presumable Mechanism for Men Infertility

Background: The aim of the present study was to investigate the in vitro effects of mercury (Hg+2), lead (Pb+2), silver (Ag+2), tin (Sn+2), bismuth (Bi+3) and indium (In+3) ions on sperm creatine kinase. Methods: creatine kinase was isolated from human sperm homogenates after chromatography on a DEAE cellulose column. Results: At 60 µg ml-1 metal concentration, 70% of the creatine kinase activi...

in vitro effect of lead, silver, tin, mercury, indium and bismuth on human sperm creatine kinase activity: a presumable mechanism for men infertility

background: the aim of the present study was to investigate the in vitro effects of mercury (hg+2), lead (pb+2), silver (ag+2), tin (sn+2), bismuth (bi+3) and indium (in+3) ions on sperm creatine kinase. methods: creatine kinase was isolated from human sperm homogenates after chromatography on a deae cellulose column. results: at 60 µg ml-1 metal concentration, 70% of the creatine kinase activi...

The Effect of Cigarette Smoking on Human Sperm Creatine Kinase Activity: As An ATP Buffering System in Sperm

In vitro effect of lead, silver, tin, mercury, indium and bismuth on human sperm creatine kinase activity: a presumable mechanism for men infertility.

BACKGROUND The aim of the present study was to investigate the in vitro effects of mercury (Hg+2), lead (Pb+2), silver (Ag+2), tin (Sn+2), bismuth (Bi+3) and indium (In+3) ions on sperm creatine kinase. METHODS creatine kinase was isolated from human sperm homogenates after chromatography on a DEAE cellulose column. RESULTS At 60 mug ml-1 metal concentration, 70% of the creatine kinase acti...

the in-vitro effects of nicotine, cotinine and leptin on sperm parameters analyzed by casa system

backgrand: cotinine (cot) is a major degradation product of nicotine (nic). the participation of leptin in female reproduction is well-established, but any role in male reproductive function is at the best tenuous. objective: the aim of this study was to evaluate the in-vitro effects of nicotine, cotinine and leptin on sperm parameters in normal semen of non-smokers fertile men. materials and m...